Isotopically Labeled Compounds
Cayman Chemical Didanosine-d2, Purity: ≥99% deuterated forms (d1-d2), 1 mg
An internal standard for the quantification of didanosine by GC- or LC-MS
Medchemexpress LLC Bis-Tris-d19 | 352534-93-1 | 99% | 100 MG
Bis-Tris-d19 is the deuterium labeled Bis-Tris. Bis-Tris is a commonly used buffer. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Alogliptin-13C,d3 benzoate | 1246817-18-4 | 98.8% | 1 MG
Alogliptin-13C,d3 benzoate is a stable isotope-labeled compound, primarily used as a tracer or an internal standard for quantitative analysis using techniques like NMR, GC-MS, or LC-MS. It is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs, which are molecules designed to exploit the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
- Application as a tracer: Can be used in studies to track metabolic pathways or drug distribution.
- Internal standard for quantitative analysis: Ideal for precise measurement in analytical methods such as NMR, GC-MS, or LC-MS due to its isotope labeling.
- PROTAC linker: Serves as a linker in the construction of PROTACs, which are bifunctional molecules that induce targeted protein degradation.
- Research use only: This product is intended for research and development purposes and not for sale to patients.
Medchemexpress LLC D-Fructose-d-1 | 57-48-7 | 5 MG
D-Fructose-d-1 is a deuterium-labeled form of D-Fructose, a naturally occurring monosaccharide found in various plants. Deuterium substitution has gained attention due to its potential to affect the pharmacokinetic and metabolic profiles of drugs. This compound is intended for research use only.
- Used as a tracer.
- Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Purity is 98.0%.
- Molecular weight is 181.16.
- Chemical formula is C6H11DO6.
- Appears as a white to off-white solid.
- Soluble in H2O at ≥ 100 mg/mL.
Cambridge Isotope Laboratories FUMARIC ACID (2,3-D2, 98%), 5 G, 24461-32-3
FUMARIC ACID (2,3-D2, 98%), 5 G, 24461-32-3
Cambridge Isotope Laboratories D-GALACTOSE (U-13C6, 99%), 0.1 G, 74134-89-7
D-GALACTOSE (U-13C6, 99%), 0.1 G, 74134-89-7
Medchemexpress LLC Sacubitrilat-d4 | 149709-44-4 | 99.3% | 387.46 | C22H21D4NO5 | 10 MG
Sacubitrilat-d4 is the deuterium-labeled form of sacubitrilat (desethyl sacubitril), provided as a stable-isotope reference standard for bioanalytical and drug-development studies. It is intended for research use as a tracer or internal standard in quantitative NMR, GC-MS, and LC-MS assays.
- Deuterium-labeled isotopologue for use as an internal standard.
- High chemical purity: 99.3%.
- Suitable for NMR, GC-MS, and LC-MS quantitative analysis.
- Supplied as a 10 mg powder for analytical applications.
- Storage: powder at -20°C (3 years) or 4°C (2 years); in solvent at -80°C (6 months).
Medchemexpress LLC N,N-dimethyl-4-(phenyldiazenyl)aniline-d5 | 1398109-08-4 | MFCD22565739 | 99.0% | 230.32 | C14H10D5N3 | 5 MG
Methyl yellow-d5 is the deuterium-labeled analogue of methyl yellow (Solvent Yellow 2), provided as a stable isotope standard for analytical and tracer applications. It is supplied as a high-purity solid reference material suitable for use as an internal standard in mass spectrometry and method development.
- High isotopic purity suitable for internal standard use.
- Compatible with mass spectrometry and liquid chromatography methods.
- Supplied as a stable, solid isotope-labeled standard for analytical workflows.
- Available in small milligram pack sizes for reference and validation.
- Documentation available includes certificate of analysis and safety data sheet for traceability.
Cambridge Isotope Laboratories URSODEOXYCHOLIC ACID (2,2,4,4-D4, 98%), 50 MG, 347841-46-7
URSODEOXYCHOLIC ACID (2,2,4,4-D4, 98%), 50 MG, 347841-46-7
Medchemexpress LLC Succinic acid-d6 | 21668-90-6 | 124.13 | 5 MG
Succinic acid-d6 is a deuterium-labeled form of succinic acid, an essential intermediate in the tricarboxylic acid cycle and a product of anaerobic metabolism. This stable isotope can be employed as a tracer and an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS. It is presented as a white to off-white solid.
- Used as a tracer in metabolic studies.
- Serves as an internal standard for quantitative analytical methods.
- Key intermediate in the tricarboxylic acid cycle.
- Product of anaerobic metabolism.
- Recommended storage at 4°C, sealed, away from moisture.
Medchemexpress LLC Zoledronic acid-d3 (zoledronate-d3) | 1134798-26-7 | 275.11 | 1 MG
Zoledronic acid-d3 (Zoledronate-d3) is the deuterium labeled Zoledronic acid. Zoledronic Acid (Zoledronate) is a third-generation bisphosphonate (BP), with potent anti-resorptive activity. Zoledronic Acid inhibits the differentiation and apoptosis of osteoclasts. Zoledronic Acid also has anti-cancer effects.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration has potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Moclobemide-d8 (Ro111163-d8) | 2309010-25-9 | >98% | 1 MG
Moclobemide-d8 (Ro111163-d8) is the deuterium-labeled version of Moclobemide. Moclobemide (Ro111163) is a brain-penetrant, reversible monoamine oxidase (MAO-A) inhibitor with an IC50 of 6.061 μM for hMAO-A. It has been shown to up-regulate the proliferation of hippocampal progenitor cells in chronically stressed mice. Stable heavy isotopes like deuterium are incorporated into drug molecules for use as tracers in drug development, potentially affecting the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Cambridge Isotope Laboratories SODIUM ACETATE (1-13C, 99%), 5 G, 23424-28-4
SODIUM ACETATE (1-13C, 99%), 5 G, 23424-28-4
Cayman Chemical Tolfenamic Acid-d4, Purity: ≥99% deuterated forms (d1-d4), CAS: 1246820-82-5, 5 mg
An internal standard for the quantification of tolfenamic acid by GC- or LC-MS
![Medchemexpress LLC L-leucine-2,3,3,4,5,5,5,5',5',5'-d10, N-[(9H-fluoren-9-ylmethoxy)carbonyl]- | 1190594-22-9 | None | 98.9% | 363.47 | C21H13D10NO4 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000213247.png-250.jpg)
Medchemexpress LLC L-leucine-2,3,3,4,5,5,5,5',5',5'-d10, N-[(9H-fluoren-9-ylmethoxy)carbonyl]- | 1190594-22-9 | None | 98.9% | 363.47 | C21H13D10NO4 | 25 MG
Fmoc-leucine-d10 is a deuterium-labeled, Fmoc-protected L-leucine supplied as a research reagent for isotopic labeling, peptide synthesis, and analytical standards. It is offered at high chemical purity for use in mass spectrometry, synthetic chemistry, and biological studies where isotopic tracers are required.
- Deuterium-labeled (d10) Fmoc-protected amino acid.
- High purity: 98.9%.
- Molecular weight 363.47 and formula C21H13D10NO4.
- Available in small research quantities such as 25 MG.
- Suitable as an MS internal standard and isotopic tracer.
- Reported to modulate PPARγ activity in biological assays.