Isotopically Labeled Compounds
Medchemexpress LLC Fluoxastrobin-d4 | 1246833-67-9 | >98.0% | 462.85 | C21H12D4ClFN4O5 | 1mg
Fluoxastrobin-d4 is the deuterium labeled Fluoxastrobin Fluoxastrobin is a fungicide agent[1]
Medchemexpress LLC Pantoprazole-d8 sodium | >98.0% | 395.42 g/mol | C16H10D8F2N3O4S | 1mg
Pantoprazole-d8 (BY1023-d8) sodium is a deuterium labeled Pantoprazole (HY-17507) Pantoprazole (BY10232) is an orally active and potent proton pump inhibitor (PPI)[1] Pantoprazole a substituted benzimidazole is a potent H /K -ATPase inhibitor with an IC50 of 6 8 M Pantoprazole improves pH stability and has anti-secretory anti-ulcer activities Pantoprazole significantly increased tumor growth delay combined with Doxorubicin (HY-15142)[3][4]
Medchemexpress LLC D-leucine-d10 | 271247-12-2 | MFCD01321412 | 99.8% | 141.23 | C6H3D10NO2 | 10mg
D-Leucine-d10 is the deuterium labeled D-Leucine D-Leucine is a more potent anti-seizure agent than L-leucine D-leucine potently terminates seizures even after the onset of seizure activity D-leucine but not L-leucine reduces long-term potentiation but had no effect on basal synaptic transmission in vitro[1]
Medchemexpress LLC Norethindrone-d6 | 2376036-05-2 | 99.9% | 1 MG
Norethindrone-d6 is a deuterium-labeled version of Norethindrone, a female progestin approved by the FDA for treating endometriosis, uterine bleeding caused by abnormal hormone levels, and secondary amenorrhea. It is also a click chemistry reagent, containing an Alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by techniques such as NMR, GC-MS, or LC-MS.
- Stable heavy isotopes incorporated into drug molecules can act as tracers for quantitation during drug development.
- Deuteration has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Doxapram-d8 | 309-29-5 | 99.5% | 1 MG
Doxapram-d8 is deuterated labeled Doxapram, which is a respiratory stimulant. It increases breathing rate and depth by acting on the brain's respiratory centers and peripheral chemoreceptors. Doxapram inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50s of 410 nM, 37 μM, 9 μM, respectively.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Alectinib-d6 | 1616374-19-6 | 98.05% | 1 MG
Alectinib-d6 is deuterium labeled Alectinib, a potent, selective, and orally available ALK inhibitor. It effectively penetrates the central nervous system (CNS) and inhibits ALK F1174L and ALK R1275Q with high potency.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Sulfamerazine-d4 | 1020719-84-9 | MFCD03425631 | 99.00% | 5 MG
Sulfamerazine-d4 is a deuterium-labeled variant of Sulfamerazine, which is classified as a sulfonamide antibacterial. Its mechanism of action involves inhibiting the bacterial synthesis of dihydrofolic acid. This is achieved by competing with para-aminobenzoic acid (PABA) for binding to dihydropteroate synthesizes.
- Deuterium labeled
- Internal standard
- Antibacterial properties
Medchemexpress LLC Trazodone-d6 (hydrochloride) | 1181578-71-1 | 99.6% | 1 MG
Trazodone-d6 (hydrochloride) is the deuterium labeled Trazodone hydrochloride.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Zoledronic acid-d3 (zoledronate-d3) | 1134798-26-7 | 275.11 | 1 MG
Zoledronic acid-d3 (Zoledronate-d3) is the deuterium labeled Zoledronic acid. Zoledronic Acid (Zoledronate) is a third-generation bisphosphonate (BP), with potent anti-resorptive activity. Zoledronic Acid inhibits the differentiation and apoptosis of osteoclasts. Zoledronic Acid also has anti-cancer effects.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration has potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Benzyl benzoate-d12 | 352431-26-6 | 99.85% | 1 MG
Benzyl benzoate-d12 is a deuterium labeled form of Benzyl benzoate. It is used as a fragrance ingredient in cosmetic products and for research into Scabies and Demodex-associated inflammatory skin conditions. This compound serves as a tracer and internal standard in quantitative analysis.
- Deuterium labeled Benzyl benzoate
- Functions as a tracer in research
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotope for drug development studies
- Potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC 2'-Deoxycytidine-13C9,15N3 | 1987883-22-6 | 99.0% | 1 MG
2'-Deoxycytidine-13C9,15N3 is a 13C and 15N-labeled 2'-Deoxycytidine. This deoxyribonucleoside can inhibit the biological effects of Bromodeoxyuridine (Brdu) and is intended for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Alpha-D-glucose-13C | 287100-64-5 | 99.4% | 25 MG
Alpha-D-glucose-13C is a 13C labeled form of alpha-D-glucose, an endogenous metabolite. This compound is intended for research use only, serving as a valuable tool in scientific studies.
- Used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Acetic acid-1-13C | 1563-79-7 | MFCD00037366 | 100.0% | 61.04 | CH313CO2H | 5g
Acetic acid-1-13C is 13C labeled Acetic acid-1
Medchemexpress LLC 2-mercaptoethanol-d6 | 203645-37-8 | 84.17 | C2D6OS | 10mg
2-Mercaptoethanol-d6 is deuterium labeled 2-Mercaptoethanol[1]
Medchemexpress LLC L-lysine-3,3,4,4,5,5,6,6-d8 hydrochloride | 344298-93-7 | 99.9% | 190.70 | C6H7D8ClN2O2 | 10 MG
L-Lysine-d8 hydrochloride is the deuterium-labeled L-enantiomer of lysine supplied as the hydrochloride salt. It is used as a stable isotope internal standard and tracer for quantitative mass spectrometry and biochemical assays.
- Deuterium-labeled (d8) for mass spectrometry standards and tracing
- Supplied as a hydrochloride solid, suitable for laboratory use
- Molecular weight 190.70, CAS 344298-93-7
- High chemical purity for analytical applications
- Available in small quantities (10 MG) for standards preparation